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RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia

Objective: Receptor-interacting protein kinase 1 (RIPK1) orchestrates the decision between cell survival and cell death in response to tumor necrosis factor (TNF) and other cytokines. Whereas the scaffolding function of RIPK1 is crucial to prevent TNF-induced apoptosis and necroptosis, its kinase ac...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Önay Veli, Öykü Kaya, Ana Beatriz Varanda, Ximena Hildebrandt, Peng Xiao, Yann Estornes, Matea Poggenberg, Yuan Wang, Manolis Pasparakis, Mathieu J.M. Bertrand, Henning Walczak, Alessandro Annibaldi, Alessandra K. Cardozo, Nieves Peltzer
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2024-09-01
Schriftenreihe:Molecular Metabolism
Schlagworte:
RIPK1
Necroptosis
TNF
Apoptosis
β-cell
Diabetes
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2212877824001194
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