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RIPK1 is dispensable for cell death regulation in β-cells during hyperglycemia

Objective: Receptor-interacting protein kinase 1 (RIPK1) orchestrates the decision between cell survival and cell death in response to tumor necrosis factor (TNF) and other cytokines. Whereas the scaffolding function of RIPK1 is crucial to prevent TNF-induced apoptosis and necroptosis, its kinase ac...

Deskribapen osoa

Gorde:
Egile Nagusiak: Önay Veli, Öykü Kaya, Ana Beatriz Varanda, Ximena Hildebrandt, Peng Xiao, Yann Estornes, Matea Poggenberg, Yuan Wang, Manolis Pasparakis, Mathieu J.M. Bertrand, Henning Walczak, Alessandro Annibaldi, Alessandra K. Cardozo, Nieves Peltzer
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2024-09-01
Saila:Molecular Metabolism
Gaiak:
RIPK1
Necroptosis
TNF
Apoptosis
β-cell
Diabetes
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S2212877824001194
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