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Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage

We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Cherry dual reporter system. Differentiation from the mouse ESC state directly into mesoderm via Wnt pathway activation was low, but augmented by treatment with AGN193109...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Ryan P. Russell, Yu Fu, Yaling Liu, Peter Maye
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2018-07-01
Rangatū:Stem Cell Research
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S1873506118301429
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