Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Cherry dual reporter system. Differentiation from the mouse ESC state directly into mesoderm via Wnt pathway activation was low, but augmented by treatment with AGN193109...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Elsevier
2018-07-01
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| Colección: | Stem Cell Research |
| Acceso en línea: | http://www.sciencedirect.com/science/article/pii/S1873506118301429 |
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