QR Code

Evaluation of molecular mechanisms of (Z)-3-(pentadec-10′-enyl)-catechol (litreol) and synthetic derivatives as inhibitors of human leukotriene biosynthesis

5-Lipoxygenase (5-LO) catalyzes the early steps of leukotriene (LT) biosynthesis, making it an attractive target for anti-inflammatory drug development. This study provides a more detailed evaluation of the molecular mechanisms and pharmacological effects of litreol (CI), a natural compound from the...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Alessia Maria Cossu, Simona Pace, Ferdinando Bruno, Lucia Abbatiello, Carmen Cerchia, Emanuele Falbo, Alejandra Catalina Muñoz Ramírez, Christian Kretzer, Laura Miek, Fabiana Troisi, Jana Gerstmeier, Pasquale Ambrosino, Silvia Zappavigna, Antonio La vecchia, Oliver Werz, Michele Caraglia, Rosanna Filosa
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Elsevier 2025-11-01
Rangatū:Redox Biology
Ngā marau:
Leukotrienes
5-Lipoxygenase
Inflammation
Litreol
Leukocytes
Chronic disease
Urunga tuihono:http://www.sciencedirect.com/science/article/pii/S2213231725003933
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!

Ngā tūemi rite