STING Promotes the Progression of ADPKD by Regulating Mitochondrial Function, Inflammation, Fibrosis, and Apoptosis
Autosomal dominant polycystic kidney disease (ADPKD) is a predominant genetic disease, which is caused by mutations in PKD genes and is associated with DNA damage in cystic cells. The intrinsic stimulator of interferon genes (STING) pathway is crucial for recognizing damaged DNA in the cytosol, trig...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
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MDPI AG
2024-09-01
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| Serier: | Biomolecules |
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| Online adgang: | https://www.mdpi.com/2218-273X/14/10/1215 |
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