Single-Cell and CellChat Resolution Identifies Collecting Duct Cell Subsets and Their Communications with Adjacent Cells in PKD Kidneys

ADPKD is a genetic disorder with a molecular complexity that remains poorly understood. In this study, we sampled renal cells to construct a comprehensive and spatiotemporally resolved gene expression atlas in whole <i>Pkd1</i> mutant polycystic mouse kidneys at single-cell resolution. We characteri...

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Principais autores:	Linda Xiaoyan Li, Xu Zhang, Hongbing Zhang, Ewud Agborbesong, Julie Xia Zhou, James P. Calvet, Xiaogang Li
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2022-12-01
Series:	Cells
Assuntos:	ADPKD single cell sequencing <i>Pkd1</i> mutation CellChat
Acceso en liña:	https://www.mdpi.com/2073-4409/12/1/45
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