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STING Promotes the Progression of ADPKD by Regulating Mitochondrial Function, Inflammation, Fibrosis, and Apoptosis

Autosomal dominant polycystic kidney disease (ADPKD) is a predominant genetic disease, which is caused by mutations in PKD genes and is associated with DNA damage in cystic cells. The intrinsic stimulator of interferon genes (STING) pathway is crucial for recognizing damaged DNA in the cytosol, trig...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Jiao Wu, Shasha Cheng, Geoffray Lee, Ewud Agborbesong, Xiaoyan Li, Xia Zhou, Xiaogang Li
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI AG 2024-09-01
Sarja:Biomolecules
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Linkit:https://www.mdpi.com/2218-273X/14/10/1215
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