Myeloid cell expression of CD200R is modulated in active TB disease and regulates Mycobacterium tuberculosis infection in a biomimetic model

A robust immune response is required for resistance to pulmonary tuberculosis (TB), the primary disease caused by Mycobacterium tuberculosis (Mtb). However, pharmaceutical inhibition of T cell immune checkpoint molecules can result in the rapid development of active disease in latently infected indi...

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Үндсэн зохиолчид:	Mohamed Ahmed, Liku B. Tezera, Nicholas Herbert, Mark Chambers, Michaela T. Reichmann, Kievershen Nargan, Henrik Kloverpris, Farina Karim, Mbali Hlatshwayo, Rajhmun Madensein, Munir Habesh, Monjural Hoque, Adrie J.C. Steyn, Paul T. Elkington, Alasdair J. Leslie
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2024-04-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	tuberculosis pulmonary infection immune checkpoint CD200 receptor innate immunity
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1360412/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!