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Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)[S]

The apical Na+-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt structure during evolution. We characterized A...

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Détails bibliographiques
Auteurs principaux: Daniël A. Lionarons, James L. Boyer, Shi-Ying Cai
Format: Artigo
Langue:Inglês
Publié: Elsevier 2012-08-01
Collection:Journal of Lipid Research
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Accès en ligne:http://www.sciencedirect.com/science/article/pii/S0022227520418577
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