Evolution of substrate specificity for the bile salt transporter ASBT (SLC10A2)[S]

The apical Na+-dependent bile salt transporter (ASBT/SLC10A2) is essential for maintaining the enterohepatic circulation of bile salts. It is not known when Slc10a2 evolved as a bile salt transporter or how it adapted to substantial changes in bile salt structure during evolution. We characterized A...

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Detalles Bibliográficos

Autores principales:	Daniël A. Lionarons, James L. Boyer, Shi-Ying Cai
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Elsevier 2012-08-01
Colección:	Journal of Lipid Research
Materias:	sodium-dependent transporter enterohepatic circulation bile acids bile alcohols taurocholic acid lamprey
Acceso en línea:	http://www.sciencedirect.com/science/article/pii/S0022227520418577
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