PGM3 insufficiency: a glycosylation disorder causing a notable T cell defect

BackgroundHypomorphic mutations in the phosphoacetylglucosamine mutase 3 (PGM3) gene cause a glycosylation disorder that leads to immunodeficiency. It is often associated with recurrent infections and atopy. The exact etiology of this condition remains unclear.ObjectiveThis study aimed to characteri...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Linlin Yang, Barbara Zerbato, Alex Pessina, Luca Brambilla, Virginia Andreani, Stefanie Frey-Jakobs, Manfred Fliegauf, Mohamed-Ridha Barbouche, Qiaoxia Zhang, Ferdinando Chiaradonna, Michele Proietti, Xin Du, Bodo Grimbacher
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-12-01
Edice:	Frontiers in Immunology
Témata:	PGM3 insufficiency infections CD4+ T cells UDP-GlcNAc glycosylation
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1500381/full
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!