The unfolded protein response in fission yeast modulates stability of select mRNAs to maintain protein homeostasis

The unfolded protein response (UPR) monitors the protein folding capacity of the endoplasmic reticulum (ER). In all organisms analyzed to date, the UPR drives transcriptional programs that allow cells to cope with ER stress. The non-conventional splicing of Hac1 (yeasts) and XBP1 (metazoans) mRNA, e...

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Váldodahkkit:	Philipp Kimmig, Marcy Diaz, Jiashun Zheng, Christopher C Williams, Alexander Lang, Tomas Aragón, Hao Li, Peter Walter
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	eLife Sciences Publications Ltd 2012-10-01
Ráidu:	eLife
Fáttát:	Unfolded Protein Response Ire1 selective mRNA decay Bip1 mRNA stabilization ER homeostasis
Liŋkkat:	https://elifesciences.org/articles/00048
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