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Transcriptional Modulation of Penicillin-Binding Protein 1b, Outer Membrane Protein P2 and Efflux Pump (AcrAB-TolC) during Heat Stress Is Correlated to Enhanced Bactericidal Action of Imipenem on Non-typeable Haemophilus influenzae

Objective: The purpose of the present study was to investigate the penicillin binding proteins (PBPs), drug influx and efflux modulations during heat stress and their effects on the bactericidal action of imipenem on non-typeable Haemophilus influenzae (NTHi).Methods: The two NTHi clinical isolates...

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主要な著者: Abdessalam Cherkaoui, Seydina M. Diene, Adrien Fischer, Stefano Leo, Patrice François, Jacques Schrenzel
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2018-01-01
シリーズ:Frontiers in Microbiology
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オンライン・アクセス:http://journal.frontiersin.org/article/10.3389/fmicb.2017.02676/full
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