Loss of STAT1 from Mouse Mammary Epithelium Results in an Increased Neu-Induced Tumor Burden

Type I and type II classes of interferons (IFNs) signal through the JAK/STAT1 pathway and are known to be important in adaptive and innate immune responses and in protection against tumors. Although STAT1 is widely considered a tumor suppressor, it remains unclear, however, if this function occurs i...

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Autors principals:	Peter J. Klover, William J. Muller, Gertraud W. Robinson, Ruth M. Pfeiffer, Daisuke Yamaji, Lothar Hennighausen
Format:	Artigo
Idioma:	Inglês
Publicat:	Elsevier 2010-11-01
Col·lecció:	Neoplasia: An International Journal for Oncology Research
Accés en línia:	http://www.sciencedirect.com/science/article/pii/S1476558610800387
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