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Synthesis of Heterocyclic Compounds Derived From Dimedone and Their Anti-tumor and Tyrosine Kinase Inhibitions

The reaction of dimedone with arylaldehydes gave the benzylidene derivatives 3a–c, the latter underwent a series of heterocyclization reactions to give fused thiophene, pyrazole isoxazole and pyridazine derivatives. The synthesized compounds were evaluated against different kinds of cancer cell line...

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Bibliographic Details
Main Authors: Rafat Mohareb, Fatma Manhi, Amal Abdelwahab
Format: Artigo
Language:Inglês
Published: Slovenian Chemical Society 2020-03-01
Series:Acta Chimica Slovenica
Subjects:
Online Access:https://journals.matheo.si/index.php/ACSi/article/view/5224
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