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Uses of Anthranilic Acid for the Synthesis of Dihydroquinazolin Derivatives with Antitumor, Anti-proliferative and Pim-1kinase Activities

The reaction of anthranilic acid with ethoxycarbonylisothiocyanate gave the ethyl 4-oxo-2-thioxo-1,2-dihydroquinazoline-3(4H)-carboxylate (4). The reaction of compound 4 with hydrazine hydrate and a-halocarbonyl derivatives was found to give either hydrazono or S-alkylated products. Heterocyclizatio...

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Detalhes bibliográficos
Principais autores: Rafat M. Mohareb, Peter A. Halim
Formato: Artigo
Idioma:Inglês
Publicado em: Slovenian Chemical Society 2018-09-01
Colecção:Acta Chimica Slovenica
Assuntos:
Acesso em linha:https://journals.matheo.si/index.php/ACSi/article/view/4146
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