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Inhibition of c3 convertase activity by hepatitis C virus as an additional lesion in the regulation of complement components.

We have previously reported that in vitro HCV infection of cells of hepatocyte origin attenuates complement system at multiple steps, and attenuation also occurs in chronically HCV infected liver, irrespective of the disease stage. However, none of these regulations alone completely impaired complem...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Hangeun Kim, Keith Meyer, Adrian M Di Bisceglie, Ranjit Ray
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2014-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC4077819?pdf=render
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