Restoration of Complement-Enhanced Neutralization of Vaccinia Virus Virions by Novel Monoclonal Antibodies Raised against the Vaccinia Virus Complement Control Protein

The vaccinia virus complement control protein (VCP) is secreted by infected cells and has been shown to inhibit complement activation through interactions with C3b/C4b. It contains four short consensus repeat (SCR) domains. It has been suggested that all four SCRs are required for VCP's activit...

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Detalhes bibliográficos
Main Authors: Isaacs, Stuart N., Argyropoulos, Emelia, Sfyroera, Georgia, Mohammad, Shamim, Lambris, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC165248/
https://ncbi.nlm.nih.gov/pubmed/12857894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.15.8256-8262.2003
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