The Hypervariable Region 1 of the E2 Glycoprotein of Hepatitis C Virus Binds to Glycosaminoglycans, but This Binding Does Not Lead to Infection in a Pseudotype System

The hypervariable region 1 (HVR1) of hepatitis C virus (HCV) E2 envelope glycoprotein is a 27-amino-acid sequence located at its N terminus. In this study, we investigated the functional role of HVR1 for interaction with the mammalian cell surface. The C-terminal truncated E2 glycoprotein was append...

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Bibliographic Details
Published in:J Virol
Main Authors: Basu, Arnab, Beyene, Aster, Meyer, Keith, Ray, Ranjit
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2004
Subjects:
Virus-Cell Interactions
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC387685/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15078928/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.78.9.4478-4486.2004
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