Integration of Immune Cell Populations, mRNA-Seq, and CpG Methylation to Better Predict Humoral Immunity to Influenza Vaccination: Dependence of mRNA-Seq/CpG Methylation on Immune Cell Populations

The development of a humoral immune response to influenza vaccines occurs on a multisystems level. Due to the orchestration required for robust immune responses when multiple genes and their regulatory components across multiple cell types are involved, we examined an influenza vaccination cohort us...

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Автори:	Gregory A. Poland, Michael T. Zimmermann, Richard B. Kennedy, Diane E. Grill, Ann L. Oberg, Krista M. Goergen, Inna G. Ovsyannikova, Iana H. Haralambieva
Формат:	Artigo
Мова:	Inglês
Опубліковано:	Frontiers Media S.A. 2017-04-01
Серія:	Frontiers in Immunology
Предмети:	influenza vaccine data mining machine learning cell sorting methylation differential expression
Онлайн доступ:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00445/full
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