Integration of Immune Cell Populations, mRNA-Seq, and CpG Methylation to Better Predict Humoral Immunity to Influenza Vaccination: Dependence of mRNA-Seq/CpG Methylation on Immune Cell Populations

The development of a humoral immune response to influenza vaccines occurs on a multisystems level. Due to the orchestration required for robust immune responses when multiple genes and their regulatory components across multiple cell types are involved, we examined an influenza vaccination cohort us...

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Autors principals:	Gregory A. Poland, Michael T. Zimmermann, Richard B. Kennedy, Diane E. Grill, Ann L. Oberg, Krista M. Goergen, Inna G. Ovsyannikova, Iana H. Haralambieva
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2017-04-01
Col·lecció:	Frontiers in Immunology
Matèries:	influenza vaccine data mining machine learning cell sorting methylation differential expression
Accés en línia:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00445/full
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