Overexpression of eis without a mutation in promoter region of amikacin- and kanamycin-resistant Mycobacterium tuberculosis clinical strain

Abstract Background Aminoglycosides such as amikacin and kanamycin are effective injectable second-line drugs for treatment of multidrug-resistant tuberculosis. Molecular mechanisms underlying aminoglycoside resistance are not well understood. We have previously identified the amikacin- and kanamyci...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Angkanang Sowajassatakul, Therdsak Prammananan, Angkana Chaiprasert, Saranya Phunpruch
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2018-07-01
coleção:	Annals of Clinical Microbiology and Antimicrobials
Assuntos:	Tuberculosis Drug resistance Aminoglycoside Efflux pump eis whiB7
Acesso em linha:	http://link.springer.com/article/10.1186/s12941-018-0285-6
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!