Overexpression of eis without a mutation in promoter region of amikacin- and kanamycin-resistant Mycobacterium tuberculosis clinical strain

Abstract Background Aminoglycosides such as amikacin and kanamycin are effective injectable second-line drugs for treatment of multidrug-resistant tuberculosis. Molecular mechanisms underlying aminoglycoside resistance are not well understood. We have previously identified the amikacin- and kanamyci...

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Autors principals:	Angkanang Sowajassatakul, Therdsak Prammananan, Angkana Chaiprasert, Saranya Phunpruch
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-07-01
Col·lecció:	Annals of Clinical Microbiology and Antimicrobials
Matèries:	Tuberculosis Drug resistance Aminoglycoside Efflux pump eis whiB7
Accés en línia:	http://link.springer.com/article/10.1186/s12941-018-0285-6
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