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Overexpression of eis without a mutation in promoter region of amikacin- and kanamycin-resistant Mycobacterium tuberculosis clinical strain

Abstract Background Aminoglycosides such as amikacin and kanamycin are effective injectable second-line drugs for treatment of multidrug-resistant tuberculosis. Molecular mechanisms underlying aminoglycoside resistance are not well understood. We have previously identified the amikacin- and kanamyci...

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Principais autores: Angkanang Sowajassatakul, Therdsak Prammananan, Angkana Chaiprasert, Saranya Phunpruch
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-07-01
Series:Annals of Clinical Microbiology and Antimicrobials
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Acceso en liña:http://link.springer.com/article/10.1186/s12941-018-0285-6
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