The phage T4 DNA ligase mediates bacterial chromosome DSBs repair as single component non-homologous end joining
DNA double-strand breaks (DSBs) are one of the most lethal forms of DNA damage that is not efficiently repaired in prokaryotes. Certain microorganisms can handle chromosomal DSBs using the error-prone non-homologous end joining (NHEJ) system and ultimately cause genome mutagenesis. Here, we demonstr...
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| Principais autores: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
KeAi Communications Co., Ltd.
2019-06-01
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| Serier: | Synthetic and Systems Biotechnology |
| Online adgang: | http://www.sciencedirect.com/science/article/pii/S2405805X19300018 |
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