Epidermal growth factor receptor ligands enriched in follicular fluid exosomes promote oncogenesis of fallopian tube epithelial cells

Abstract Background Incessant ovulation is the main etiologic factor of ovarian high-grade serous carcinomas (HGSC), which mostly originate from the fallopian tube epithelium (FTE). Receptor tyrosine kinase (RTK) ligands essential for follicle development and ovulation wound repair were abundant in...

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Autori principali:	Aye Aye Khine, Pao-Chu Chen, Ying-Hsi Chen, Sung-Chao Chu, Hsuan-Shun Huang, Tang-Yuan Chu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	BMC 2024-12-01
Serie:	Cancer Cell International
Soggetti:	Ovulation High-grade serous carcinomas (HGSC) Epidermal growth factor receptor (EGFR) Follicular fluid (FF) exosome
Accesso online:	https://doi.org/10.1186/s12935-024-03614-9
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