Ovulation releases G-CSF to induce peritoneal neutrophil influx and netosis, facilitating peritoneal seeding of high-grade serous carcinoma

Introduction: High-grade serous ovarian cancer (HGSC), the most lethal subtype of epithelial ovarian cancer (EOC), often originates from serous tubal intraepithelial carcinoma (STIC) and is typically diagnosed at advanced stages. However, the mechanisms underlying the dissemination of STIC cells int...

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Hauptverfasser:	Tang-Yuan Chu, Pao-Chu Chen, Aye Aye Khine, Ying-Hsi Chen, Sung-Chao Chu, Hsuan-Shun Huang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-12-01
Schriftenreihe:	Neoplasia: An International Journal for Oncology Research
Schlagworte:	High-grade serous carcinoma Serous tubal intraepithelial carcinomas Ovulation G-CSF Neutrophil extracellular traps (NET)
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S1476558625001162
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