Activator protein-1 (AP-1) inhibition prevents endothelial to mesenchymal transition in diabetes-associated atherosclerosis: a translational study

Abstract Background Endothelial to mesenchymal transition (EndMT), the transformation of endothelial cells into a mesenchymal-like state, is regulated by various factors, including transcription factors such as activator protein 1 (AP-1). While recent studies have confirmed the role of EndMT in athe...

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Detalhes bibliográficos

Principais autores:	Abdul Waheed Khan, Misbah Aziz, Karly C Sourris, Jairo P Cortes, Tomasz J Block, Aozhi Dai, Scott Maxwell, Jun Okabe, Emma Pyper, Francesco Paneni, Mark E Cooper, Karin AM Jandeleit-Dahm
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-01-01
coleção:	Cardiovascular Diabetology
Assuntos:	AP-1 complex T-5224 EndMT Diabetes associated atherosclerosis
Acesso em linha:	https://doi.org/10.1186/s12933-025-03060-5
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