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Activator protein-1 (AP-1) inhibition prevents endothelial to mesenchymal transition in diabetes-associated atherosclerosis: a translational study

Abstract Background Endothelial to mesenchymal transition (EndMT), the transformation of endothelial cells into a mesenchymal-like state, is regulated by various factors, including transcription factors such as activator protein 1 (AP-1). While recent studies have confirmed the role of EndMT in athe...

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Principais autores: Abdul Waheed Khan, Misbah Aziz, Karly C Sourris, Jairo P Cortes, Tomasz J Block, Aozhi Dai, Scott Maxwell, Jun Okabe, Emma Pyper, Francesco Paneni, Mark E Cooper, Karin AM Jandeleit-Dahm
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2026-01-01
Series:Cardiovascular Diabetology
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Acceso en liña:https://doi.org/10.1186/s12933-025-03060-5
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