In-silico, in-vitro, and proteomics analyses on repurposed drugs in targeting the small GTPase, Rho subfamily protein (Rho GTPase), and putative Rho GTPase-activating protein (RhoGAP) of Giardia lamblia

Giardia lamblia is a globally prevalent protozoan responsible for Giardiasis, an intestinal disease commonly treated with nitroimidazoles such as metronidazole, tinidazole, and albendazole. However, increasing drug resistance has reduced treatment efficacy. Rho GTPase and its regulator, putative Rho...

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التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Nurhana Jasni, Khairul Bariyyah Abd. Halim, Wong Weng Kin, Darren Lau, Clifford Young, Peter Hoffmann, Nurulhasanah Othman
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	Elsevier 2025-12-01
سلاسل:	Journal of Genetic Engineering and Biotechnology
الموضوعات:	Giardia lamblia Rho-GTPase activating protein Rho GTPase Repurposed Drug Proteomics In-silico
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S1687157X25001179
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!