Notum deacylates octanoylated ghrelin
Objectives: The only proteins known to be modified by O-linked lipidation are Wnts and ghrelin, and enzymatic removal of this post-translational modification inhibits ligand activity. Indeed, the Wnt-deacylase activity of Notum is the basis of its ability to act as a feedback inhibitor of Wnt signal...
Збережено в:
| Автори: | , , , , , , , , , , |
|---|---|
| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2021-07-01
|
| Серія: | Molecular Metabolism |
| Предмети: | |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2212877821000417 |
| Теги: |
Немає тегів, Будьте першим, хто поставить тег для цього запису!
|