Interaction of transcription factor AP‐2 gamma with proto‐oncogene PELP1 promotes tumorigenesis by enhancing RET signaling

A significant proportion of estrogen receptor‐positive (ER+) breast cancer (BC) initially responds to endocrine therapy but eventually evolves into therapy‐resistant BC. Transcription factor AP‐2 gamma (TFAP2C) is a known regulator of ER activity, and high expression of TFAP2C is associated with a d...

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Autori principali:	Junhao Liu, Zexuan Liu, Mengxing Li, Weiwei Tang, Uday P. Pratap, Yiliao Luo, Kristin A. Altwegg, Xiaonan Li, Yi Zou, Hong Zhu, Gangadhara R. Sareddy, Suryavathi Viswanadhapalli, Ratna K. Vadlamudi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Wiley 2021-04-01
Serie:	Molecular Oncology
Soggetti:	breast cancer coactivator PELP1 TFAP2C therapy resistance
Accesso online:	https://doi.org/10.1002/1878-0261.12871
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