Targeting FAP/CAFs to rewire immune-excluded and resistant tumor niches
Immune checkpoint blockade (ICB) has reshaped cancer therapy, yet many solid tumors remain immune-excluded, with cytotoxic T cells trapped in stromal regions and unable to access malignant nests. In these settings, cancer-associated fibroblasts (CAFs) and their extracellular matrix programs act as a...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Frontiers Media S.A.
2026-06-01
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| Sarja: | Frontiers in Pharmacology |
| Aiheet: | |
| Linkit: | https://www.frontiersin.org/articles/10.3389/fphar.2026.1812674/full |
| Tagit: |
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