Unleashing the potential of combining FGFR inhibitor and immune checkpoint blockade for FGF/FGFR signaling in tumor microenvironment

Abstract Background Fibroblast growth factors (FGFs) and their receptors (FGFRs) play a crucial role in cell fate and angiogenesis, with dysregulation of the signaling axis driving tumorigenesis. Therefore, many studies have targeted FGF/FGFR signaling for cancer therapy and several FGFR inhibitors...

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Principais autores:	Ruiwen Ruan, Li Li, Xuan Li, Chunye Huang, Zhanmin Zhang, Hongguang Zhong, Shaocheng Zeng, Qianqian Shi, Yang Xia, Qinru Zeng, Qin Wen, Jingyi Chen, Xiaofeng Dai, Jianping Xiong, Xiaojun Xiang, Wan Lei, Jun Deng
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2023-03-01
סדרה:	Molecular Cancer
נושאים:	Fibroblast growth factor receptor Immune checkpoint blockade Tumor microenvironment Immunotherapy
גישה מקוונת:	https://doi.org/10.1186/s12943-023-01761-7
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!