Sodium-glucose cotransporter 2 inhibitors, inflammation, and heart failure: a two-sample Mendelian randomization study

Abstract Background Sodium-glucose cotransporter 2 (SGLT-2) inhibitors are increasingly recognized for their role in reducing the risk and improving the prognosis of heart failure (HF). However, the precise mechanisms involved remain to be fully delineated. Evidence points to their potential anti-in...

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Hauptverfasser:	Wenqin Guo, Lingyue Zhao, Weichao Huang, Jing Chen, Tingting Zhong, Shaodi Yan, Wei Hu, Fanfang Zeng, Changnong Peng, Hongbing Yan
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-04-01
Schriftenreihe:	Cardiovascular Diabetology
Schlagworte:	Heart failure Sodium-glucose cotransporter 2 inhibition Inflammatory biomarkers Mendelian randomization
Online-Zugang:	https://doi.org/10.1186/s12933-024-02210-5
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