SGLT2 inhibition, circulating metabolites, and atrial fibrillation: a Mendelian randomization study

Abstract Background Sodium-glucose cotransporter 2 (SGLT2) inhibitors have shown promise in reducing the risk of atrial fibrillation (AF). However, the results are controversial and the underlying metabolic mechanism remains unclear. Emerging evidence implied that SGLT2 inhibitors have extra benefic...

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Bibliografische Detailangaben

Hauptverfasser:	Jiang Li, Yuefeng Yu, Ying Sun, Bowei Yu, Xiao Tan, Bin Wang, Yingli Lu, Ningjian Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-10-01
Schriftenreihe:	Cardiovascular Diabetology
Schlagworte:	Atrial fibrillation Sodium-glucose cotransporter 2 inhibition Circulating metabolites Mendelian randomization
Online-Zugang:	https://doi.org/10.1186/s12933-023-02019-8
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