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Sodium-glucose cotransporter protein 2 inhibition, plasma proteins, and ischemic stroke: A mediation Mendelian randomization and colocalization study

Purpose: To determine the effect of the sodium-glucose cotransporter protein 2 (SGLT2) inhibition on ischemic stroke (IS) and investigate the circulating proteins that mediate the effects of SGLT2 inhibition on IS. Methods: The effects of SGLT2 inhibition on IS were evaluated using two-sample Mendel...

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Principais autores: Zhiqing Chen, Hongmei Meng, Yujin Guo, Huaiyu Sun, Wuqiong Zhang, Yu Guo, Shuai Hou
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2025-01-01
Series:Journal of Stroke and Cerebrovascular Diseases
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S1052305724005792
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