A retrospective multicenter study on clinical and serological parameters in patients with MuSK myasthenia gravis with and without general immunosuppression

IntroductionMuscle-specific kinase (MuSK)- myasthenia gravis (MG) is caused by pathogenic autoantibodies against MuSK that correlate with disease severity and are predominantly of the IgG4 subclass. The first-line treatment for MuSK-MG is general immunosuppression with corticosteroids, but the effec...

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Principais autores:	Inga Koneczny, Marina Mané-Damas, Shenghua Zong, Sander De Haas, Saif Huda, Daan van Kruining, Jan Damoiseaux, Anna De Rosa, Michelangelo Maestri, Melania Guida, Peter Molenaar, Philip Van Damme, Andreas Fichtenbaum, Thomas Perkmann, Marc De Baets, Konstantinos Lazaridis, Vasiliki Zouvelou, Socrates Tzartos, Roberta Ricciardi, Mario Losen, Pilar Martinez-Martinez
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2024-04-01
Colecção:	Frontiers in Immunology
Assuntos:	MuSK myasthenia gravis IgG4 corticosteroids prednisolone prednisone IgG4 autoimmune disease
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1325171/full
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