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Multi-gene precision editing tool using CRISPR-Cas12a/Cpf1 system in Ogataea polymorpha

Abstract Background Ogataea polymorpha, a non-conventional methylotrophic yeast, has demonstrated significant potential for heterologous protein expression and the production of high-value chemicals and biopharmaceuticals. However, the lack of precise and efficient genome editing tools severely hind...

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I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Senqin Hou, Shibin Yang, Wenqin Bai
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2025-01-01
Rangatū:Microbial Cell Factories
Ngā marau:
Urunga tuihono:https://doi.org/10.1186/s12934-025-02654-8
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