Optimizing a CRISPR-Cpf1-based genome engineering system for Corynebacterium glutamicum
Abstract Background Corynebacterium glutamicum is an important industrial strain for the production of a diverse range of chemicals. Cpf1 nucleases are highly specific and programmable, with efficiencies comparable to those of Cas9. Although the Francisella novicida (Fn) CRISPR-Cpf1 system has been...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BMC
2019-03-01
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| Serie: | Microbial Cell Factories |
| Soggetti: | |
| Accesso online: | http://link.springer.com/article/10.1186/s12934-019-1109-x |
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