Metabolic Promiscuity of an Orphan Small Alarmone Hydrolase Facilitates Bacterial Environmental Adaptation

ABSTRACT Small alarmone hydrolases (SAHs) are alarmone metabolizing enzymes found in both metazoans and bacteria. In metazoans, the SAH homolog Mesh1 is reported to function in cofactor metabolism by hydrolyzing NADPH to NADH. In bacteria, SAHs are often identified in genomes with toxic alarmone syn...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Danny K. Fung, Kaihong Bai, Jin Yang, Xiaoli Xu, David M. Stevenson, Daniel Amador-Noguez, Laixin Luo, Jue D. Wang
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2022-12-01
Цуврал:	mBio
Нөхцлүүд:	(p)ppGpp NADH nucleotide metabolism plant pathogens stress response
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/mbio.02422-22
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!