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Pleiotropic Effects of Bacterial Small Alarmone Synthetases: Underscoring the Dual-Domain Small Alarmone Synthetases in Mycobacterium smegmatis

The nucleotide alarmone (p)ppGpp, signaling the stringent response, is known for more than 5 decades. The cellular turnover of the alarmone is regulated by RelA/SpoT homolog (RSH) superfamily of enzymes. There are long RSHs (RelA, SpoT, and Rel) and short RSHs [small alarmone synthetases (SAS) and s...

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Библиографические подробности
Главные авторы: Sushma Krishnan, Dipankar Chatterji
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2020-10-01
Серии:Frontiers in Microbiology
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Online-ссылка:https://www.frontiersin.org/article/10.3389/fmicb.2020.594024/full
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