Mechanism and therapeutic potential of targeting cGAS-STING signaling in neurological disorders
Abstract DNA sensing is a pivotal component of the innate immune system that is responsible for detecting mislocalized DNA and triggering downstream inflammatory pathways. Among the DNA sensors, cyclic GMP-AMP synthase (cGAS) is a primary player in detecting cytosolic DNA, including foreign DNA from...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
BMC
2023-11-01
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| Collection: | Molecular Neurodegeneration |
| Sujets: | |
| Accès en ligne: | https://doi.org/10.1186/s13024-023-00672-x |
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