CDC42 supports HBV entry by NTCP translocation to the plasma membrane and macropinocytosis

Abstract CDC42 is a member of Rho GTPase family that regulates various biological processes and its activity can be hijacked by invading pathogens. Here, we discovered that the level of active CDC42 in hepatocytes positively correlates with the entry capacity of hepatitis B virus (HBV). Mechanistica...

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Bibliografski detalji

Glavni autori:	Shuzhi Cui, Wei Gao, Yuxin Chen, Yi Xu, Zhifang Li, Yu Wei, Yaming Jiu
Format:	Artigo
Jezik:	Inglês
Izdano:	Springer Nature 2025-09-01
Serija:	EMBO Reports
Teme:	CDC42 Hepatitis B Virus Macropinocytosis Sodium Taurocholate Cotransporting Polypeptide Virus Entry
Online pristup:	https://doi.org/10.1038/s44319-025-00581-8
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