The amphiregulin- epidermal growth factor receptor axis as a therapeutic target in sepsis

The Epidermal Growth Factor Receptor (EGFR) and its ligand, amphiregulin (AREG) are critical for epithelial cell proliferation but their important role in inflammation and infection is increasingly described. We recently discovered that the EGFR ligand, amphiregulin, could identify a cohort of infan...

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Principais autores:	Rebecca Walsh, Timothy Arthur Chandos Snow, Alexandra Z. Martinez, David Brealey, Mervyn Singer, Abhishek Das, Nishkantha Arulkumaran, University College London Hospitals Critical Care Research Team
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2025-09-01
叢編:	Frontiers in Immunology
主題:	sepsis intensive care unit amphiregulin epidermal growth factor receptor monocyte lymphocyte
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1638244/full
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