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Antibacterial activity of a DNA topoisomerase I inhibitor versus fluoroquinolones in Streptococcus pneumoniae.

The DNA topoisomerase complement of Streptococcus pneumoniae is constituted by two type II enzymes (topoisomerase IV and gyrase), and a single type I enzyme (topoisomerase I). These enzymes maintain the DNA topology, which is essential for replication and transcription. While fluoroquinolones target...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Myriam V Valenzuela, Mirian Domenech, Patricia Mateos-Martínez, Fernando González-Camacho, Adela G de la Campa, Maria Teresa García
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science (PLoS) 2020-01-01
Cyfres:PLoS ONE
Mynediad Ar-lein:https://doi.org/10.1371/journal.pone.0241780
Tagiau: Ychwanegu Tag
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