FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments
Abstract Tau aggregation into amyloid fibers based on the cross-beta structure is a hallmark of several Tauopathies, including Alzheimer Disease (AD). Trans-cellular propagation of Tau with pathological conformation has been suggested as a key disease mechanism. This is thought to cause the spreadin...
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| Principais autores: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2020-07-01
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| Colecção: | Molecular Neurodegeneration |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s13024-020-00389-1 |
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