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Characteristics of tau oligomers

In Alzheimer disease (AD) and other tauopathies, microtubule-associated protein tau becomes hyperphosphorylated, undergoes conformational changes, aggregates, eventually becoming neurofibrillary tangles (NFTs). As accumulating evidence suggests that NFTs themselves may not be toxic, attention is now...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Yan eRen, Naruhiko eSahara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2013-07-01
Schriftenreihe:Frontiers in Neurology
Schlagworte:
Online-Zugang:http://journal.frontiersin.org/Journal/10.3389/fneur.2013.00102/full
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