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Tau Secretion: Good and Bad for Neurons

In Alzheimer’s disease (AD), neurofibrillary tangles (NFTs), lesions composed of hyperphosphorylated and aggregated tau, spread from the transentorhinal cortex to the hippocampal formation and neocortex. Growing evidence indicates that tau pathology propagates trans-synaptically, implying that patho...

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Principais autores: Camille Pernègre, Antoine Duquette, Nicole Leclerc
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neuroscience
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Acceso en liña:https://www.frontiersin.org/article/10.3389/fnins.2019.00649/full
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